diff --git a/platform/chromium/vapi-background.js b/platform/chromium/vapi-background.js
index 7c270038a..3014ca2f3 100644
--- a/platform/chromium/vapi-background.js
+++ b/platform/chromium/vapi-background.js
@@ -75,6 +75,12 @@ vAPI.storage = chrome.storage.local;
 vAPI.browserSettings = {
     webRTCSupported: undefined,
 
+    // https://github.com/gorhill/uBlock/issues/875
+    // Must not leave `lastError` unchecked.
+    noopCallback: function() {
+        void chrome.runtime.lastError;
+    },
+
     // https://github.com/gorhill/uBlock/issues/533
     // We must first check wether this Chromium-based browser was compiled
     // with WebRTC support. To do this, we use an iframe, this way the
@@ -121,30 +127,35 @@ vAPI.browserSettings = {
             return;
         }
 
-        // Older version of Chromium do not support this setting.
-        if ( typeof chrome.privacy.network.webRTCMultipleRoutesEnabled !== 'object' ) {
-            return;
+        var cp = chrome.privacy, cpi = cp.IPHandlingPolicy, cpn = cp.network;
+
+        // Older version of Chromium do not support this setting, and is
+        // marked as "deprecated" since Chromium 48.
+        if ( typeof cpn.webRTCMultipleRoutesEnabled === 'object' ) {
+            try {
+                cpn.webRTCMultipleRoutesEnabled.set({
+                    value: !!setting,
+                    scope: 'regular'
+                }, this.noopCallback);
+            } catch(ex) {
+                console.error(ex);
+            }
         }
 
-        try {
-            chrome.privacy.network.webRTCMultipleRoutesEnabled.set({
-                value: !!setting,
-                scope: 'regular'
-            }, function() {
-                void chrome.runtime.lastError;
-            });
-        } catch(ex) {
-            console.error(ex);
+        // This setting became available in Chromium 48.
+        if ( typeof cpn.webRTCIPHandlingPolicy === 'object' ) {
+            try {
+                cpn.webRTCIPHandlingPolicy.set({
+                    value: !!setting ? cpi.DEFAULT : cpi.DEFAULT_PUBLIC_INTERFACE_ONLY,
+                    scope: 'regular'
+                }, this.noopCallback);
+            } catch(ex) {
+                console.error(ex);
+            }
         }
     },
 
     set: function(details) {
-        // https://github.com/gorhill/uBlock/issues/875
-        // Must not leave `lastError` unchecked.
-        var callback = function() {
-            void chrome.runtime.lastError;
-        };
-
         for ( var setting in details ) {
             if ( details.hasOwnProperty(setting) === false ) {
                 continue;
@@ -155,7 +166,7 @@ vAPI.browserSettings = {
                     chrome.privacy.network.networkPredictionEnabled.set({
                         value: !!details[setting],
                         scope: 'regular'
-                    }, callback);
+                    }, this.noopCallback);
                 } catch(ex) {
                     console.error(ex);
                 }
@@ -166,7 +177,7 @@ vAPI.browserSettings = {
                     chrome.privacy.websites.hyperlinkAuditingEnabled.set({
                         value: !!details[setting],
                         scope: 'regular'
-                    }, callback);
+                    }, this.noopCallback);
                 } catch(ex) {
                     console.error(ex);
                 }