diff --git a/lib/Transforms/Instrumentation/PGOInstrumentation.cpp b/lib/Transforms/Instrumentation/PGOInstrumentation.cpp
index 4884a499019..787f098869f 100644
--- a/lib/Transforms/Instrumentation/PGOInstrumentation.cpp
+++ b/lib/Transforms/Instrumentation/PGOInstrumentation.cpp
@@ -334,7 +334,7 @@ struct PGOIndirectCallSiteVisitor
 
   void visitCallInst(CallInst &I) {
     CallSite CS(&I);
-    if (CS.getCalledFunction() || !CS.getCalledValue())
+    if (CS.getCalledFunction() || !CS.getCalledValue() || I.isInlineAsm())
       return;
     IndirectCallInsts.push_back(&I);
   }
diff --git a/test/Transforms/PGOProfile/inlineasm.ll b/test/Transforms/PGOProfile/inlineasm.ll
new file mode 100644
index 00000000000..70b9c081d10
--- /dev/null
+++ b/test/Transforms/PGOProfile/inlineasm.ll
@@ -0,0 +1,16 @@
+; RUN: opt < %s -pgo-instr-gen -S | FileCheck %s
+
+target datalayout = "e-m:o-i64:64-f80:128-n8:16:32:64-S128"
+target triple = "x86_64-apple-macosx10.12.0"
+
+define i32 @main() {
+entry:
+; CHECK: call void @llvm.instrprof.increment
+; CHECK-NOT: ptrtoint void (i8*)* asm sideeffect
+; CHECK-NOT: call void @llvm.instrprof.value.profile
+; CHECK: tail call void asm sideeffect 
+  tail call void asm sideeffect "", "imr,~{memory},~{dirflag},~{fpsr},~{flags}"(i8* undef) #0
+  ret i32 0
+}
+
+attributes #0 = { nounwind }