diff --git a/Utilities/bin_patch.cpp b/Utilities/bin_patch.cpp
index 730a7336cb..66ae7e7bb1 100644
--- a/Utilities/bin_patch.cpp
+++ b/Utilities/bin_patch.cpp
@@ -71,6 +71,11 @@ std::string patch_engine::get_patch_config_path()
 #endif
 }
 
+std::string patch_engine::get_imported_patch_path()
+{
+	return fs::get_config_dir() + "patches/imported_patch.yml";
+}
+
 static void append_log_message(std::stringstream* log_messages, const std::string& message)
 {
 	if (log_messages)
@@ -461,7 +466,7 @@ void patch_engine::append_global_patches()
 	load(m_map, fs::get_config_dir() + "patches/patch.yml");
 
 	// Imported patch.yml
-	load(m_map, fs::get_config_dir() + "patches/imported_patch.yml");
+	load(m_map, get_imported_patch_path());
 }
 
 void patch_engine::append_title_patches(const std::string& title_id)
@@ -729,6 +734,11 @@ bool patch_engine::save_patches(const patch_map& patches, const std::string& pat
 
 	for (const auto& [hash, container] : patches)
 	{
+		if (container.patch_info_map.empty())
+		{
+			continue;
+		}
+
 		out << YAML::Newline << YAML::Newline;
 		out << hash << YAML::BeginMap;
 		out << "Patches" << YAML::BeginMap;
@@ -793,6 +803,27 @@ bool patch_engine::import_patches(const patch_engine::patch_map& patches, const
 	return false;
 }
 
+bool patch_engine::remove_patch(const patch_info& info)
+{
+	patch_engine::patch_map patches;
+
+	if (load(patches, info.source_path))
+	{
+		if (patches.find(info.hash) != patches.end())
+		{
+			auto& container = patches[info.hash];
+
+			if (container.patch_info_map.find(info.description) != container.patch_info_map.end())
+			{
+				container.patch_info_map.erase(info.description);
+				return save_patches(patches, info.source_path);
+			}
+		}
+	}
+
+	return false;
+}
+
 patch_engine::patch_config_map patch_engine::load_config(bool& enable_legacy_patches)
 {
 	enable_legacy_patches = true; // Default to true
diff --git a/Utilities/bin_patch.h b/Utilities/bin_patch.h
index 3a2956be06..645962bc80 100644
--- a/Utilities/bin_patch.h
+++ b/Utilities/bin_patch.h
@@ -74,6 +74,9 @@ public:
 	// Returns the directory in which patch_config.yml is located
 	static std::string get_patch_config_path();
 
+	// Returns the filepath for the imported_patch.yml
+	static std::string get_imported_patch_path();
+
 	// Load from file and append to specified patches map
 	// Example entry:
 	//
@@ -108,6 +111,9 @@ public:
 	// Create or append patches to a file
 	static bool import_patches(const patch_map& patches, const std::string& path, std::stringstream* log_messages = nullptr);
 
+	// Remove a patch from a file
+	static bool remove_patch(const patch_info& info);
+
 	// Load patch_config.yml
 	static patch_config_map load_config(bool& enable_legacy_patches);
 
diff --git a/rpcs3/rpcs3qt/patch_manager_dialog.cpp b/rpcs3/rpcs3qt/patch_manager_dialog.cpp
index 34a5b1ad93..74f56b1f44 100644
--- a/rpcs3/rpcs3qt/patch_manager_dialog.cpp
+++ b/rpcs3/rpcs3qt/patch_manager_dialog.cpp
@@ -101,7 +101,7 @@ void patch_manager_dialog::load_patches()
 	}
 }
 
-static QList<QTreeWidgetItem*> find_children_by_data(QTreeWidgetItem* parent, const QList<QPair<int /*role*/, const QVariant& /*data*/>>& criteria)
+static QList<QTreeWidgetItem*> find_children_by_data(QTreeWidgetItem* parent, const QList<QPair<int /*role*/, QVariant /*data*/>>& criteria)
 {
 	QList<QTreeWidgetItem*> list;
 
@@ -203,7 +203,7 @@ void patch_manager_dialog::populate_tree()
 			const QString q_description = QString::fromStdString(description);
 			QString visible_description = q_description;
 
-			const auto match_criteria = QList<QPair<int, const QVariant&>>() << QPair(description_role, q_description) << QPair(persistance_role, true);
+			const auto match_criteria = QList<QPair<int, QVariant>>() << QPair(description_role, q_description) << QPair(persistance_role, true);
 
 			// Add counter to leafs if the name already exists due to different hashes of the same game (PPU, SPU, PRX, OVL)
 			if (const auto matches = find_children_by_data(serial_level_item, match_criteria); matches.count() > 0)
@@ -436,6 +436,37 @@ void patch_manager_dialog::on_custom_context_menu_requested(const QPoint &pos)
 				{
 					gui::utils::open_dir(info.source_path);
 				});
+
+				if (info.source_path == patch_engine::get_imported_patch_path())
+				{
+					menu->addSeparator();
+
+					QAction* remove_patch = new QAction("Remove Patch");
+					menu->addAction(remove_patch);
+					connect(remove_patch, &QAction::triggered, this, [info, this](bool)
+					{
+						const auto answer = QMessageBox::question(this, tr("Remove Patch?"),
+							tr("Do you really want to remove the selected patch?\nThis action is immediate and irreversible!"));
+
+						if (answer != QMessageBox::StandardButton::Yes)
+						{
+							return;
+						}
+
+						if (patch_engine::remove_patch(info))
+						{
+							patch_log.success("Successfully removed patch %s: %s from %s", info.hash, info.description, info.source_path);
+							refresh(); // Refresh before showing the dialog
+							QMessageBox::information(this, tr("Success"), tr("The patch was successfully removed!"));
+						}
+						else
+						{
+							patch_log.error("Could not remove patch %s: %s from %s", info.hash, info.description, info.source_path);
+							refresh(); // Refresh before showing the dialog
+							QMessageBox::warning(this, tr("Failure"), tr("The patch could not be removed!"));
+						}
+					});
+				}
 			}
 		}
 	}
@@ -493,7 +524,7 @@ void patch_manager_dialog::dropEvent(QDropEvent* event)
 		return;
 	}
 
-	for (const auto drop_path : drop_paths)
+	for (const QString& drop_path : drop_paths)
 	{
 		const auto path = drop_path.toStdString();
 		patch_engine::patch_map patches;
@@ -505,7 +536,7 @@ void patch_manager_dialog::dropEvent(QDropEvent* event)
 
 			if (do_import)
 			{
-				static const std::string imported_patch_yml_path = fs::get_config_dir() + "patches/imported_patch.yml";
+				static const std::string imported_patch_yml_path = patch_engine::get_imported_patch_path();
 
 				log_message.clear();